Acellular Dermal Matrices: Advancing Reconstructive and Regenerative Medicine
Acellular Dermal Matrices (ADM) have emerged as a transformative innovation in the fields of reconstructive and regenerative medicine. These biologic materials are derived from human or animal skin, processed to remove cellular components while preserving the structural framework of the dermis. The result is a biocompatible scaffold that supports tissue integration, healing, and regeneration without provoking a significant immune response.
The development of ADM has revolutionized surgical practices, particularly in areas where soft tissue repair or reinforcement is required. One of the key applications is in breast reconstruction following mastectomy. ADM provides structural support for implants, improves aesthetic outcomes, and reduces complications such as capsular contracture. By integrating with the patient’s own tissues, ADM creates a more natural feel and appearance compared to traditional synthetic materials.
Another significant use of ADM is in hernia repair. Traditionally, synthetic meshes were the standard, but…

